Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. Last Revised - 09/15/2019. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. It can cause your blood pressure to become dangerously low. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Important information about all medicines, Notes on Isosorbide mononitrate dose and side-effects info, https://patient.info/medicine/isosorbide-mononitrate-elantan-imdur-isotard-monomax-tardisc-xismox, Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets, Carmil XL; Chemydur XL; Elantan LA; Imdur; Isib XL; Ismo; Isodur XL; Isotard XL; Modisal XL; Monomax SR; Monomil XL; Nyzamac SR; Relosorb XL; Tardisc XL; Trangina XL; Xismox XL; Zemon XL, Tablets, modified-release (longer-acting) tablets, and modified-release (longer-acting) capsules, Ask your doctor or pharmacist to recommend a suitable painkiller. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. GoodRx works to make its website accessible to all, including those with disabilities. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . It will not treat an angina attack that has already begun. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If this worries you, talk to your doctor or pharmacist about other options. Drug interactions may change how your medications work or increase your risk for serious side effects. Along with its needed effects, a medicine may cause some unwanted effects. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Copyright, 2023. Headache and weakness of left side (both arm and leg) may suggest a brain pathology. To view a report comparing 3 (or more) medications, please sign in or create an account. You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Store in a cool, dry place, away from direct heat and light. tell your doctor if you may be dehydrated, if you have recently had a heart attack, or if you have or have ever had heart failure, low blood pressure, or hypertrophic cardiomyopathy (thickening of the heart muscles). No, that's not true all the time. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. The herb licorice may lower warfarin levels and can add to digoxin's effects. Consult your doctor for more details. Real test is coronary angiography. you should know that you may experience headaches every day during your treatment with isosorbide. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. If you become pregnant while taking isosorbide, call your doctor. It works by . What are the side effects of Isosorbide Mononitrate ? By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Patient is a UK registered trade mark. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Journal of the American College of Cardiology. Nitroglycerin has an average rating of Browse all drugs on eHealthMe. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. It works by relaxing and widening blood vessels so blood can flow more easily to the heart.This medication will not relieve chest pain once it occurs. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Methods: In a randomized, double-blind, crossover study, 89 patients with stable angina pectoris were studied to compare two different dosage strategies of isosorbide-5-mononitrate (5-ISMN). 55 ratings on Drugs.com. Portions of this document last updated: Feb. 01, 2023. Accessed Sept. 7, 2022. Some don't work well with prescription medicines. Please note that only the generic name of each medication is listed below. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. 46 ratings on Drugs.com. Do infrared saunas have any health benefits? Is it safe to drive while on this medicine? When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Even if the medication is working, you may experience some unwanted side effects. This content does not have an Arabic version. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. 19 are major, 174 are moderate, and 2 are minor. https://naturalmedicines.therapeuticresearch.com. Use of herbal products and potential interactions in patients with cardiovascular diseases. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. https://naturalmedicines.therapeuticresearch.com. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. The https:// ensures that you are connecting to the You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Take your next dose at the regular time. This medication belongs to a class of drugs known as nitrates. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. This product may contain inactive ingredients, which can cause allergic reactions or other problems. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Do not keep out-of-date or unwanted medicines. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. All rights reserved. https://naturalmedicines.therapeuticresearch.com. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. Do not take two doses together to make up for a missed dose. The effects of this exposure on a nursing infant are unknown. Garlic. I took this for 4 days, and my headaches were unbearable. Side effects : headache, mild dizziness We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Do not store in the bathroom. Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. This product is available in the following dosage forms: There is a problem with it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. 88 ratings on Drugs.com. Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. Which drugs or supplements interact with isosorbide mononitrate? Before All Rights Reserved. This is called a medicine interaction. The most common side-effect is headache. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. People with kidney problems should be able to take the usual dose of isosorbide mononitrate (Monoket). Isosorbide mononitrate. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. You need to take it every day in order for it to work. Isosorbide mononitrate has an average rating of Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. Ask your pharmacist for a list of the ingredients. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Minimally clinically significant. In case of overdose, call the poison control helpline at 1-800-222-1222. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. https://naturalmedicines.therapeuticresearch.com. information is beneficial, we may combine your email and website usage information with Liperoti R, et al. Isosorbide mononitrate (Monoket) can cause some serious health issues. The .gov means its official. Sept. 26, 2022. Take care, thanks. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. from the best health experts in the business. Accessed Sept. 7, 2022. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. If your chest pain attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. Talk to your doctor if you are using marijuana (cannabis). tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. Conclusions: It does not work fast enough to relieve the pain of an angina attack that has already started. May also be prescribed off label for Esophageal Spasm. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Accessed Sept. 7, 2022. Longer-acting tablets and capsules are taken once daily in the morning. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). Other side effects not listed may also occur in some patients. Prescribed for Angina, Anal Fissure and Isosorbide is in a class of medications called vasodilators. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Some of these medicine interactions can be risky. It is important to take the drug at the same times each day. Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. Otherwise, call a poison control center right away. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). Call your doctor if you have any unusual problems while you are taking this medication.